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<title>Ðàçíûå ïðåïàðàòû - Áîäèáèëäèíã íà MAX-BODY. Îò ëþáèòåëÿ äî ìîíñòðà</title>
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	<title>Áåòà-àëàíèí</title>
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	<description>&amp;beta;-Alanine, beta-alanine</description>
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	<pubDate>Mon, 04 Apr 2011 21:17:12 +0300</pubDate>
	<yandex:full-text>Áåòà-àëàíèí (&amp;beta;-Alanine èëè beta-alanine) - ÿâëÿåòñÿ ïðèðîäíîé áåòà àìèíîêèñëîòîé, â êîòîðîé àìèíîãðóïïà íàõîäèòñÿ â &amp;beta;-ïîëîæåíèè. Íàçâàíèå â IUPAC: 3-àìèíîïðîïèîíîâàÿ êèñëîòà.  îòëè÷èå îò ñâîåãî ñòåðè÷åñêîãî àíàëîãà - &amp;alpha;-àëàíèíà, &amp;beta;-àëàíèí íå èìååò õèðàëüíîãî öåíòðà.&amp;nbsp;&amp;beta;-àëàíèí íå âêëþ÷àåòñÿ â ñèíòåç êðóïíûõ áåëêîâ è ýíçèìîâ.  îðãàíèçìå áåòà-àëàíèí îáðàçóåòñÿ â ðåçóëüòàòå äåãðàäàöèè äèãèäðîóðàöèëà è êàðíîçèíà. Âõîäèò â ñîñòàâ åñòåñòâåííûõ áåëêîâ êàðíîçèíà è àíñåðèíà, à òàê æå ÿâëÿåòñÿ ÷àñòüþ ïàíòîòåíîâîé êèñëîòû (âèòàìèí Â5), êîòîðàÿ âõîäèò â ñîñòàâ êîýíçèìà À.  îðãàíèçìå áåòà-àëàíèí ìåòàáîëèçèðóåòñÿ äî óêñóñíîé êèñëîòû.
Áèîëîãè÷åñêîå äåéñòâèå áåòà-àëàíèíèíà 
Áåòà-àëàíèí, ïî äàííûì èññëåäîâàíèé [1], êàê ñîñòàâëÿþùàÿ êàðíîçèíà, ÿâëÿåòñÿ âàæíûì áóôåðîì â ìûøå÷íîé òêàíè, êîòîðûé ïðåïÿòñòâóåò çàêèñëåíèþ ñðåäû âî âðåìÿ èíòåíñèâíûõ óïðàæíåíèé. Åãî âêëàä â îáùóþ áóôåðíóþ ñèñòåìó êîëåáëåòñÿ îò 10 äî 20%.
Áåòà-àëàíèí â ñïîðòå
 èññëåäîâàíèè, ïðåäñòàâëåííîì äîêòîðîì Jeff Stout íà åæåãîäíîé êîíôåðåíöèè Îáùåñòâà ñïîðòèâíîãî ïèòàíèÿ â 2005 ãîäó, áûëî ðàññìîòðåíî âëèÿíèå áåòà-àëàíèíà (1,6-3,2 ã â äåíü) íà ðàáî÷óþ ìîùíîñòü â ðàéîíå ïîðîãà óòîìëåíèÿ ó íåòðåíèðîâàííûõ ìóæ÷èí.  ðåçóëüòàòå áûëî çàôèêñèðîâàíî 9%-íîå óâåëè÷åíèå ïîðîãà óòîìëåíèÿ è áûëî âûäâèíóòî ïðåäïîëîæåíèå î òîì, ÷òî ïðèåì áåòà-àëàíèíà îòîäâèãàåò ìîìåíò íàñòóïëåíèÿ íåéðîìûøå÷íîãî óòîìëåíèÿ.

Óâåëè÷åíèå âûíîñëèâîñòè çà ñ÷åò ïðèåìà áåòà-àëàíèíà (êàðíîçèíà)
Áåòà-àëàíèí ïðîÿâëÿåòñÿ ñåáÿ, ãëàâíûì îáðàçîì, êàê âîññòàíîâèòåëü ìûøå÷íîé òêàíè è ìîùíûé áóôåð, ïîýòîìó áîëüøå âñåãî îí íåîáõîäèì ñïîðòñìåíàì, ñòàëêèâàþùèìñÿ ñ àíàýðîáíûìè íàãðóçêàìè, â òîì ÷èñëå è áîäèáèëäèðàì, òàê êàê çà ñ÷åò óâåëè÷åíèÿ âûíîñëèâîñòè, áåòà-àëàíèí êîñâåííî ñïîñîáñòâóåò óâåëè÷åíèþ èíòåíñèâíîñòè òðåíèðîâîê, à çíà÷èò è ðîñòó ìóñêóëàòóðû. Äëÿ ëåãêîàòëåòîâ áåòà-àëàíèí íå ïðåäñòàâëÿåò öåííîñòè, êàê ïîêàçàëè ïîñëåäíèå èññëåäîâàíèÿ. [2]
Ñïîðòèâíîå ïèòàíèå ñ áåòà-àëàíèíîì 
Êîëè÷åñòâî êàðíîçèíà â îðãàíèçìå íàõîäèòñÿ â ïðÿìîì ñîîòíîøåíèè ñ êîëè÷åñòâîì äîñòóïíîãî áåòà-àëàíèíà. Ñïîðòèâíîå ïèòàíèå ñ áåòà-àëàíèíîì ïîçâîëÿåò óâåëè÷èòü óðîâåíü êàðíîçèíà â ìûøöàõ, êàê ñëåäñòâèå ñíèçèòü óòîìëÿåìîñòü ó àòëåòîâ è óâåëè÷èòü îáùóþ ðàáîòó ìûøö âî âðåìÿ òðåíèðîâîê. [3] [4] Áåòà-àëàíèí äîñòóïåí â âèäå ðàñòâîðîâ è ïîðîøêîâ â æåëàòèíîâûõ êàïñóëàõ. Íàèáîëåå ïîïóëÿðíûå ñïîðòèâíûå äîáàâêè, ñîäåðæàùèå áåòà-àëàíèí: 1. USPlabs Jack3d2. VPX NO Shotgun3. Controlled Labs White Flood4. Double-T Sports NO Beta 5. Controlled Labs Purple Wraath6. CM2 Alpha îò SAN Ðåêîìåíäóåìûå äîçû áåòà-àëàíèíà îò 400 äî 800ìã, ïðèíèìàþòñÿ ðåãóëÿðíî ÷åðåç îäèíàêîâûå ïðîìåæóòêè âðåìåíè (8 ÷àñîâ), â òå÷åíèè 5-10 íåäåëü.  èññëåäîâàíèÿõ áûëî îïðåäåëåíî, ÷òî ýòî îïòèìàëüíûå ðåæèì ïðèåìà, ïîñëå êîòîðîãî óðîâåíü êàðíîçèíà â ìûøöàõ ïîâûøàëñÿ â ñðåäíåì íà 80%. [5]
Âëèÿíèå íà çäîðîâüå&amp;nbsp;
Îòíîñèòåëüíî âûñîêèå äîçû áåòà-àëàíèíà (áîëåå 50 ìã/êã) ìîãóò âûçûâàòü ïàðåñòåçèè, êîòîðûå ñâÿçàíû ñ ðàçäðàæåíèåì ïåðèôåðè÷åñêèõ íåðâîâ.  Ïîýòîìó åñëè ó âàñ âîçíèêëè îùóùåíèÿ ïîêàëûâàíèÿ, òî ýòî àáñîëþòíî íîðìàëüíî è ãîâîðèò ëèøü î òîì, ÷òî ïðîäóêò ðàáîòàåò. Åñëè ýòè îùóùåíèÿ äîñòàâëÿþò âàì íåóäîáñòâî - ñíèçüòå äîçó.&amp;nbsp;Äàííîå âåùåñòâî åùå äàëåêî íå äî êîíöà èçó÷åíî, è âîçìîæíû äðóãèå ïîáî÷íûå ðåàêöèè, êîòîðûå â íàñòîÿùåå âðåìÿ íå âûÿâëåíû, ïîýòîìó íå ðåêîìåíäóåòñÿ ïðåâûøàòü ðåêîìåíäóåìûå äîçèðîâêè.
Ññûëêè

Mannion AF, Jakeman PM, Dunnett M, Harris RC, and Willan PLT (1992) Carnosine and anserine concentrations in the quadriceps femoris muscle of healthy humans. Eur. J. Appl. Physiol. 64:47-50.&amp;nbsp;
J Appl Physiol. Beta-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters. 2007 Nov;103(5):1736-43. Epub 2007 Aug 9.&amp;nbsp;
Derave W, Ozdemir MS, Harris R, Pottier A, Reyngoudt H, Koppo K, Wise JA, Achten E. (August 9 2007). &quot;Beta-alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters&quot;. J Appl Physiol 103: 1736.&amp;nbsp;
Hill CA, Harris RC, Kim HJ, Harris BD, Sale C, Boobis LH, Kim CK, Wise JA. (2007). &quot;Influence of beta-alanine supplementation on skeletal muscle carnosine concentrations and high intensity cycling capacity&quot;. Amino Acids 32 (2): 225&amp;ndash;33.&amp;nbsp;
Harris RC, Tallon MJ, Dunnett M, Boobis L, Coakley J, Kim HJ, Fallowfield JL, Hill CA, Sale C, and Wise JA (2006) The absorption of orally supplied &amp;beta;-alanine and its effect on muscle carnosine synthesis in human vastus lateralis. Amino Acids. 30:279-289.
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	<title>Ñèíòîë</title>
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	<description>Ñèíòîë, Sinthol, Synthol</description>
	<category>Ðàçíûå ïðåïàðàòû</category>
	<author>43facog6D</author>
	<pubDate>Mon, 23 Nov 2009 01:17:17 +0200</pubDate>
	<yandex:full-text>Âñå íà÷àëîñü ñ òîãî, ÷òî â íà÷àëå 90-õ, íåìåöêèé õèìèê è êóëüòóðèñò Êðèñ Êëàðê çàäóìàë ñîçäàòü àíàëîã ïðåïàðàòà ýöèêëåí (Ýöèêëåí àòëåòû âêàëûâàþò â îòäåëüíûå ìûøöû è ìûøå÷íûå ãðóïïû ïåðåä ñîðåâíîâàíèÿìè äëÿ âðåìåííîãî ýôôåêòà óâåëè÷åíèÿ ìûøå÷íûõ îáúåìîâ, èíúåêöèè î÷åíü áîëåçíåííû è ê òîìó æå ýôôåêò âðåìåííûé è &quot;äåðæèòñÿ&quot; âñåãî íåñêîëüêî äíåé).
Êàçàëîñü, Êëàðê ïîñòàâèë ïåðåä ñîáîé íåâûïîëíèìóþ çàäà÷ó - ñîçäàòü àíàëîã Ýöèêëåíà, äåéñòâèå êîòîðîãî áû äëèëîñü ãîäàìè. È åìó ýòî óäàëîñü! Ýòîò ñîñòàâ îí íàçâàë Ñèíòîë - òàê íàçûâàåòñÿ îäíà èç ñàìûõ ìîùíûõ òåõíîëîãèé ÿäåðíîãî ñèíòåçà. Íî âûÿñíèëîñü, ÷òî íàçâàíèå óæå çàïàòåíòîâàíî â íåñêîëüêèõ ñòðàíàõ, ïðè÷åì íå â îáëàñòè ÿäåðíîé ôèçèêè, à â ìåäèöèíå. Ïîýòîìó ïðèäóìàëè íîâóþ òîðãîâóþ ìàðêó &quot;Pump N&#039;Pose&quot; (Êà÷àéñÿ è ïîçèðóé). Ïîä ýòîé ìàðêîé îí è ïðîäàåòñÿ ïî âñåìó ìèðó â îãðîìíûõ îáúåìàõ. Îäíàêî ñðåäè êóëüòóðèñòîâ ïðî÷íî óêîðåíèëîñü íàçâàíèå Ñèíòîë, ïîä êîòîðûì íà÷àëèñü ïåðâûå ïðîäàæè. Ñåãîäíÿ îíî òàêæå ïðèæèëîñü â êà÷êîâñêîé ëåêñèêå êàê ìåòàí èëè äåêà. Ìèëëèîíû êóëüòóðèñòîâ â íàøè äíè áîãîòâîðÿò èçîáðåòåíèå Êëàðêà.  ñàìîì äåëå, ìíîãèå ëè ñïîñîáíû &quot;âûðàñòèòü&quot; ðóêè ïî 50 ñì, äàæå ïðèìåíÿÿ îãðîìíûå äîçû ñòåðîèäîâ. À ñ Ñèíòîëîì ýòî çàïðîñòî! Âäîáàâîê, Ñèíòîë íå èìååò ïîáî÷íûõ ýôôåêòîâ ñòåðîèäîâ.
Òàê, ÷òî æå ïðåäñòàâëÿåò èç ñåáÿ ñèíòîë? Ñèíòîë - ïðåïàðàò ìåæìûøå÷íîé æèðîâîé êèñëîòû. Ïðåäñòàâëÿåò èç ñåáÿ ñèíòåòè÷åñêîå ìàñëî, ââîäèìîå â ìûøöó, êîòîðóþ íóæíî óâåëè÷èòü. Ïðèíöèï ðàáîòû ïðåïàðàòà çàêëþ÷àåòñÿ â òîì, ÷òî îí ïðîíèêàåò â ïðîìåæóòêè ìåæäó ìûøå÷íûìè âîëîêíàìè (êàê áû &quot;ïðîïèòûâàÿ&quot; åå), ãäå îí è îñòàåòñÿ, âûçûâàÿ òàêèì îáðàçîì åå óâåëè÷åíèå. Îêîëî 30 ïðîöåíòîâ ïðåïàðàòà ïî÷òè íåìåäëåííî ðàñùåïëÿåòñÿ ôåðìåíòàìè îðãàíèçìà è âûâîäèòñÿ â îáìåí âåùåñòâ, êàê îáû÷íûé æèð. Êîòîðûé ðàáîòàåò êàê áûñòðî ñãîðàþùåå òîïëèâî äëÿ ìûøö, òî åñòü íå ïðîèñõîäèò æèðîâûõ îòëîæåíèé. Îñòàâøèåñÿ 70 ïðîöåíòîâ ñîõðàíÿþòñÿ â ìûøöàõ íà ïðîòÿæåíèè 3-5 ëåò, ïîñòåïåííî ðàñïàäàÿñü íà ýëåìåíòàðíûå æèðîâûå ôðàãìåíòû, óòèëèçèðóåìûå ïå÷åíüþ. Ìíîãèå êóëüòóðèñòû óòâåðæäàþò, ÷òî ïðåïàðàò äåéñòâóåò äîëüøå - äî 8 ëåò.
Dan Duchaine (ñòåðîèäíûé &quot;ãóðó&quot; Muscle Media 2000) íåäàâíî ïðîâîäèë àíàëèç îáðàçöà Ñèíòîëà è ïðèøåë ê âûâîäó, ÷òî ïðåïàðàò ñîñòîèò íà 85 ïðîöåíòîâ èç æèðíûõ êèñëîò: â îñíîâíîì òèïà C8, íåêîòîðîå êîëè÷åñòâî C10, è îêîëî 3% C12 (áóêâà C è öèôðû ïîëå íåå ïîêàçûâàþò, äëèíó æèðîâîé öåïî÷êè - êîðîòêàÿ, ñðåäíÿÿ èëè äëèííàÿ). Ïðåïàðàò òàêæå ñîäåðæèò 7.5% ëèäîêàèíà (lidocaine) - îáåçáîëèâàþùåå ñðåäñòâî è 7.5% áåíçèë - àëêîãîëü (benzyl - alcohol).
Èçãîòîâèòåëè ïðåïàðàò óòâåðæäàþò, ÷òî íè÷åãî ïëîõîãî îáû÷íûå æèðû ïðè÷èíèòü íå ìîãóò. Áîëåå òîãî, æèðû, êîòîðûå îôèöèàëüíî ïðèçíàíû êàê êðàéíå ïîëåçíûå äëÿ çäîðîâüÿ. Îäíàêî ñàìè ïî ñåáå èíúåêöèè ëþáîãî ÷óæåðîäíîãî ñîñòàâà ìîãóò áûòü î÷åíü îïàñíû. Åñëè âû ñëó÷àéíî ïîïàäåòå èãëîé â îäèí èç êðîâåíîñíûõ ñîñóäîâ, ýòî ÷ðåâàòî ñåðüåçíûì ïîâðåæäåíèåì òêàíåé &quot;íèæå ïî òå÷åíèþ êðîâîòîêà&quot;. Æèðîâîé ñîñòàâ ñîáèðàåòñÿ â øàð è ìîæåò íàìåðòâî çàêóïîðèò êðîâîòîê. Íàðóøåíèå êðîâîîáðàùåíèÿ âûçîâåò ñåðäå÷íûé ïðèñòóï, à åñëè âîâðåìÿ íå îêàçàòü ìåäèöèíñêóþ ïîìîùü, òî è ñìåðòü. Îäíàêî ïîêà íå áûëî îôèöèàëüíî çàðåãèñòðèðîâàíî íè îäíîãî ñìåðòåëüíîãî ñëó÷àÿ, ñâÿçàííîãî ñ ïðèìåíåíèåì Ñèíòîëà.
Ðóêîâîäñòâî ÈÔÁÁ îäíîçíà÷íî ïðèðàâíÿëî Ñèíòîë ê ñòåðîèäàì è îôèöèàëüíî çàïðåòèëî åãî èñïîëüçîâàíèå. Ëþáîïûòíî, ÷òî ïðîäàâöû Ñèíòîëà âî âñåõ ñòðàíàõ, êàê âïðî÷åì, ê åãî ñîçäàòåëü, ÷òî íàçûâàåòñÿ, õîäÿò ïî ëåçâèþ áðèòâû. Åñëè áû Ñèíòîë ïðèâëåê âíèìàíèå êàê ïðåïàðàò äëÿ âíóòðèìûøå÷íûõ èíúåêöèé, òî áûë áû áåçóñëîâíî çàïðåùåí âî âñåõ ñòðàíàõ, è ïðåæäå âñåãî â Ãåðìàíèè, ãäå áûë èçîáðåòåí. Âîò ïîýòîìó Ñèíòîë ââîçÿò è ïðîäàþò êàê... &quot;ìàñëî äëÿ ïîçèðîâàíèÿ&quot;.
Ýôôåêòèâíàÿ äîçèðîâêà: â òå÷åíèå ïåðâûõ 20 äíåé åæåäíåâíî ïî 1 ìë. Åùå 10 äíåé - ïî 2 ìë. Ïîòîì ïî 3 ìë åæåäíåâíî, ïîêà ìûøöà áóäåò óâåëè÷èâàòü ñâîé îáúåì. Êîãäà ðîñò îáúåìà ïðåêðàòèòñÿ, â òå÷åíèå 30 äíåé ïî 1 ìë åæåäíåâíî. Åùå 30 äíåé - ïî 1 ìë äâàæäû â äåíü. Ïîòîì ïî 1 ìë â íåäåëþ â òå÷åíèå 1 ìåñÿöà. Òîëüêî ïîñëå ïðîõîæäåíèÿ òàêîãî êóðñà ïðèðîñò îáúåìà ìûøöû ñòàíîâèòñÿ ïîñòîÿííûì, è ìûøöà íå óìåíüøàåòñÿ. Ïîñëå òðåõ íåäåëüíîãî êóðñà ðóêè óâåëè÷èâàþòñÿ íà 5-6 ñì è äåðæàò îáúåì äîâîëüíî äîëãî. ×åðåç 4 ìåñÿöà êóðñ íàäî ïîâòîðèòü ñíîâà: âîçìîæíî, óäàñòñÿ äîáèòüñÿ íîâîãî ïðèáàâëåíèÿ îáúåìà .
Öåíà íàñòîÿùåãî Ñèíòîëà êîëåáëåòñÿ â ïðåäåëàõ 300-400 äîëëàðîâ çà áóòûëî÷êó.</yandex:full-text>
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